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EtherFlyer is a decentralized exchange started in 2018. It maintains trading with pairs structured against BTC and ETH. 
Liquid is a new exchange that was based on Japanese Quoinex and Qryptos exchanges in 2018. Liquid’s World Book combines a global network of liquidity sources by leveraging Quoine's Matching Engine, Smart Order Routing, and Cross Currency Conversion Engine technologies.
ShapeShift was founded by Eric Voorhees in 2014. Online exchanger based in the Swiss town of Geneva. The main function is the quick conversion of bitcoin and popular altcoins with the highest possible protection of transactions. The peculiarity of the exchange is that client assets are not stored on the site itself. And this, undoubtedly, increases the security of the service, although it somewhat impoverishes the functionality. You can find more information on the ShapeShift team and the project here.