IOST is currently based on cryptocurrency Ethereum protocol.
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EOSDT is a first decentralized USD-pegged stable coin launched as part of the Equilibrium network. A 1:1 parity with USD is protected. This coin is represented on number of exchange platforms, including decentralized exchanges and HITBTC, Bequant, Bancor, etc. It’s also supported by many wallets. You can buy EOSDT for USD with bank card, using the MoonPay service.